CHE-1

WormBase ID: WBGene00000483

WormBase description: Is an ortholog of human ZNF500 and ZSCAN4 (zinc finger and SCAN domain containing 4). Exhibits RNA polymerase II regulatory region sequence-specific DNA binding activity. Is involved in several processes, including response to lithium ion; response to magnesium ion; and response to methionine. Is expressed in ASEL and ASER.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-AAAGTTTGGCACCTGTAGCG-3'

Strain name: SYS570

Cross: OP677 x JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs677 (che-1::TY1::EGFP::3xFLAG + unc-119(+))

Expression pattern: Expressed after bean stage

Lineage expression pattern

350 stage

600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): NA


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: AST-1, CEBP-1, DAF-19, DMD-5, EGL-18, ETS-5, GMEB-2, HLH-30, K09A11.1, LIM-7, NHR-102, RCOR-1, SEL-8, SWSN-7, TTX-1, UNC-62, ZTF-6

Targeted by: NA

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: CEBP-1, DAF-19, DMD-5, ETS-5, GMEB-2, HLH-30, RCOR-1, SWSN-7, TTX-1, UNC-62

Targeted by: NA