WormBase ID: WBGene00003167 WormBase description: Is an ortholog of human LHX1 (LIM homeobox 1) and LHX5 (LIM homeobox 5). Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and transcription factor binding activity. Is involved in several processes, including mechanosensory behavior; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding activity; and positive regulation of transcription by RNA polymerase II. Localizes to RNA polymerase II transcription factor complex. Is expressed in touch receptor neurons; ventral nerve cord; and vulva. |
Reporter verification: Verified by PCR and sequencing |
Strain name: SYS71 Cross: OP55 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs55 (mec-3::TY1::EGFP::3xFLAG(92C12) + unc-119(+)) |
Expression pattern: Expressed after bean stage |
Lineage expression pattern 350 stage |
600 stage |
3D expression pattern 4-cells 8-cells 15-cells 28-cells ~50-cells ~100-cells ~200-cells ~350-cells ~500-cells ~600-cells 600-cells bean-stage |
Inferred TF relationships Based on expression similarity (strong, medium, weak): NA Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined) Targeting: ARID-1, CEH-9, ETS-5, LIM-7, LIN-1, NHR-102, POP-1, SYD-9, UNC-39 Targeted by: NA |
Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined) Targeting: ARID-1, ETS-5, POP-1, SYD-9 Targeted by: NA |