WormBase ID: WBGene00001252 WormBase description: Is an ortholog of human GATA4 (GATA binding protein 4) and GATA5 (GATA binding protein 5). Exhibits double-stranded DNA binding activity. Localizes to nucleus. Is expressed in intestine; marginal cell; pm6; and pm7. Human ortholog(s) of this gene are implicated in several diseases, including Down syndrome; congenital heart disease (multiple); and hypoparathyroidism-deafness-renal disease syndrome. |
Reporter verification: Verified by PCR and sequencing |
Strain name: SYS171 Cross: OP111 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs111 (elt-4::TY1::EGFP::3xFLAG + unc-119(+)) |
Expression pattern: Non-specific |
Lineage expression pattern 350 stage ![]() ![]() |
600 stage ![]() |
3D expression pattern ![]() 4-cells ![]() 8-cells ![]() 15-cells ![]() 28-cells ![]() ~50-cells ![]() ~100-cells ![]() ~200-cells ![]() ~350-cells ![]() ~500-cells ![]() ~600-cells ![]() 600-cells ![]() bean-stage |
Inferred TF relationships Based on expression similarity (strong, medium, weak): NA Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined) Targeting: ARID-1, ATHP-1, BLMP-1, CEBP-1, DAF-12, ETS-5, HLH-30, NHR-102, ZAG-1, ZFH-2, ZTF-6 Targeted by: DSC-1 |
Targeting: ARID-1, BLMP-1, CEBP-1, ETS-5, HLH-30, ZFH-2 Targeted by: NA |