BED-3

WormBase ID: WBGene00009133

WormBase description: Is an ortholog of human ZBED1 (zinc finger BED-type containing 1); ZBED4 (zinc finger BED-type containing 4); and ZBED6 (zinc finger BED-type containing 6). Exhibits RNA polymerase II regulatory region sequence-specific DNA binding activity. Is involved in molting cycle; regulation of cell division; and vulval cell fate specification. Is expressed in M lineage cell; hypodermal cell; and vulval cell.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-AAACTGTATTTCCGTTGTTCAATAG-3'

Strain name: SYS563

Cross: OP651 x JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs651 (bed-3::TY1::EGFP::3xFLAG + unc-119(+))

Expression pattern: Non-specific

Lineage expression pattern

350 stage

600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): CEH-31, UNC-39, UNC-120, F23B12.7


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: AST-1, CEH-2, DAF-19, DMD-5, ETS-5, K09A11.1, LIM-7, MDL-1, NHR-102, RCOR-1

Targeted by: ELT-3, PROS-1, SPTF-1, ZIP-8, BLMP-1

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: CEH-2, DAF-19, DMD-5, ETS-5, MDL-1, RCOR-1

Targeted by: SPTF-1, ZIP-8, BLMP-1, ELT-3