AHR-1

WormBase ID: WBGene00000096

WormBase description: Is an ortholog of human AHR (aryl hydrocarbon receptor). Exhibits DNA binding activity and RNA polymerase II transcription factor binding activity. Is involved in negative regulation of locomotion and response to xenobiotic stimulus. Is expressed in ALML; ALMR; RMEL; RMER; and neurons.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-ATCAGTAACTCAAATCTCGGTAAG-3'

Strain name: SYS571

Cross: OP562 x JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs562 (ahr-1::TY1::EGFP::3xFLAG + unc-119(+))

Expression pattern: Expressed after bean stage

Lineage expression pattern

350 stage

600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): NA


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: ETS-5, K09A11.1, LIM-7, MDL-1, NHR-102, RCOR-1

Targeted by: CEH-22, CEH-34, COG-1, LIN-32, NFYA-1, PHA-4, TBX-2, UNC-55, UNC-62, ZIP-8

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: ETS-5, MDL-1, RCOR-1

Targeted by: CEH-22, COG-1, LIN-32, NFYA-1, PHA-4, TBX-2, UNC-55, UNC-62, ZIP-8