UNC-55

WormBase ID: WBGene00006790

WormBase description: Is an ortholog of human NR2F1 (nuclear receptor subfamily 2 group F member 1). Is predicted to have several functions, including DNA-binding transcription factor activity; nuclear receptor transcription coactivator activity; and transcription factor binding activity. Is expressed in motor neurons; somatic nervous system; and spicule muscle.

KI information: GFP knockin at C-terminus

Reporter verification:Verified by comparing expression pattern to the literature (Zhou and Walthall, 1998)

Strain name: SYS749

KI background: JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; unc-55 (hzhCR2 [unc-55::gfp]) I

Expression pattern: Expressed after bean stage

Lineage expression pattern

350 stage

600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): NA


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: AHR-1, ALY-1, ATFS-1, ATHP-1, CAMT-1, CEBP-1, CEH-13, CEH-20, CEH-34, CEH-38, CEH-39, CEH-40, CEH-43, CEH-44, CES-2, CRH-2, DAF-12, DAF-3, EFL-1, EFL-3, EGL-44, EGL-46, EGRH-1, ELT-1, ETS-5, FOS-1, GMEB-1, HBL-1, HLH-1, HLH-11, HLH-30, LIM-7, LIN-1, LIN-13, LIN-22, LIN-39, LSY-2, M03D4.4, MDL-1, MEF-2, MEP-1, MML-1, NHR-10, NHR-12, NHR-25, NHR-35, NHR-49, REF-1, RNT-1, SDZ-38, SEM-4, SKN-1, SNAI-1, SPR-4, SWSN-7, SYD-9, TAG-68, TLP-1, UNC-130, UNC-3, UNC-37, UNC-4, UNC-62, VAB-15, Y75B8A.6, ZAG-1, ZTF-11, ZTF-6

Targeted by: BLMP-1, CEH-36

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: AHR-1, ALY-1, ATFS-1, ATHP-1, CAMT-1, CEBP-1, CEH-13, CEH-20, CEH-34, CEH-39, CEH-40, CEH-43, CEH-5, CEH-74, CES-2, CRH-2, EFL-1, EGL-44, EGL-46, ELT-1, ETS-5, GMEB-1, HLH-1, HLH-30, LIN-13, LIN-39, LSY-2, MDL-1, MEF-2, MEP-1, MML-1, NFYC-1, NHR-10, NHR-12, NHR-35, NHR-49, SEM-4, SKN-1, SNAI-1, SWSN-7, SYD-9, TAG-68, TLP-1, UNC-130, UNC-37, UNC-4, UNC-62, VAB-15, ZAG-1

Targeted by: BLMP-1