CEH-38

WormBase ID: WBGene00000459

WormBase description: Is an ortholog of human ONECUT1 (one cut homeobox 1); ONECUT2 (one cut homeobox 2); and ONECUT3. Is predicted to have DNA binding activity. Is expressed in several structures, including body wall musculature; excretory cell; intestine; neurons; and somatic nervous system.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-CTCGGGAAATGCAACAAACA-3'

Strain name: SYS162

Cross: OP241 x JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs241 (ceh-38::TY1::EGFP::3xFLAG(92C12) + unc-119(+))

Expression pattern: Non-specific

Lineage expression pattern

350 stage




600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): NA


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: no-data

Targeted by: CEH-14, CEH-18, CEH-19, CEH-2, CEH-31, CEH-34, CEH-36, CEH-39, CEH-48, CEH-6, CEH-83, CND-1, COG-1, DVE-1, ELT-2, ETS-4, FKH-10, HLH-1, HLH-30, HLH-8, HMG-4, LIN-13, LSY-2, M03D4.4, MEP-1, MLS-2, NFYA-1, NHR-12, PAX-1, PHA-4, PROS-1, REF-2, RNT-1, SEM-2, SPTF-1, TBX-2, UNC-120, UNC-42, UNC-55, UNC-62, UNC-86, ZTF-11, AHA-1, ALY-2, BLMP-1, C16A3.4, CEH-8, CEH-82, CEH-90, DPL-1, DSC-1, EFL-1, EGL-13, ELT-3, FKH-4, FKH-8, FOS-1, IRX-1, LIN-39, MDL-1, MEF-2, NHR-85, PAX-3, SKN-1, SOX-4, SWSN-7, UNC-130, UNC-30, VAB-15, ZAG-1

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: no-data

Targeted by: CEH-39, CEH-48, PAX-1