WormBase ID: WBGene00022861 WormBase description: Is an ortholog of human SATB2 (SATB homeobox 2). Exhibits chaperone binding activity. Is involved in embryo development and mitochondrial unfolded protein response. Localizes to nuclear transcription factor complex. Is expressed in several structures, including amphid neurons; rectum; somatic nervous system; tail; and vulva. Human ortholog(s) of this gene are implicated in chromosome 2q32-q33 deletion syndrome. |
Reporter verification: Verified by PCR and sequencing |
Strain name: SYS165 Cross: OP398 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs398 (dve-1::TY1::EGFP::3xFLAG + unc-119(+)) |
Expression pattern: Lineage-specific, Intestine-specific |
Lineage expression pattern 350 stage   |
600 stage  |
3D expression pattern  4-cells  8-cells  15-cells  28-cells  ~50-cells  ~100-cells  ~200-cells  ~350-cells  ~500-cells  ~600-cells  600-cells  bean-stage |
Inferred TF relationships Based on expression similarity (strong, medium, weak): ELT-2, ELT-7, END-1, END-3, PQM-1, MDL-1, NHR-232, ZFH-2, FOS-1, NHR-102, CEH-2, ODD-2, NHR-12, AST-1, PHA-4, TBX-9, HBL-1, CEH-45, M03D4.4, CES-2 Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined) Targeting: MDL-1, ZFH-2, FOS-1, NHR-102, PHA-4, ATFS-1, ATHP-1, CEBP-1, CEH-38, DAF-19, DAF-3, DMD-5, EFL-1, EGL-18, EGRH-1, ELT-6, ETS-5, HLH-11, HLH-30, K09A11.1, LIM-7, LIN-13, LIN-31, MEP-1, NHR-49, SKN-1, SMA-2, SWSN-7, UNC-37, Y75B8A.6, ZTF-6 Targeted by: ELT-2, PHA-4, BLMP-1, CEH-83, ELT-1, HAM-2, HMG-4, LSY-2, NFYA-1, ZIP-8, SKN-1 |
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Targeting: MDL-1, ZFH-2, ATFS-1, ATHP-1, CEBP-1, DAF-19, DMD-5, EFL-1, ETS-5, HLH-30, LIN-13, LIN-31, MEP-1, NHR-49, SKN-1, SMA-2, SWSN-7, UNC-37, Y75B8A.6 Targeted by: ELT-2, PHA-4, BLMP-1, CEH-83, ELT-1, HAM-2, HMG-4, LSY-2, NFYA-1, ZIP-8, SKN-1 |
