WormBase ID: WBGene00001974 WormBase description: Is an ortholog of human SSRP1 (structure specific recognition protein 1). Is predicted to have histone binding activity and nucleosome binding activity. Is involved in pharynx development and regulation of embryonic development. Localizes to nucleus. Is expressed in several structures, including coelomocyte; head muscle; neurons; somatic cell; and somatic nervous system. Human ortholog(s) of this gene are implicated in mitochondrial DNA depletion syndrome 15. |
Reporter verification: Verified by whole-genome sequencing |
Strain name: SYS226 Cross: OP660 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs660 (hmg-4::TY1::EGFP::3xFLAG + unc-119(+)) |
Expression pattern: Transient-expression |
Lineage expression pattern 350 stage ![]() ![]() |
600 stage ![]() |
3D expression pattern ![]() 4-cells ![]() 8-cells ![]() 15-cells ![]() 28-cells ![]() ~50-cells ![]() ~100-cells ![]() ~200-cells ![]() ~350-cells ![]() ~500-cells ![]() ~600-cells ![]() 600-cells ![]() bean-stage |
Inferred TF relationships Based on expression similarity (strong, medium, weak): NA Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined) Targeting: BLMP-1, CAMT-1, CEBP-1, CEH-13, CEH-20, CEH-38, CEH-39, CEH-43, CES-2, CRH-2, DAF-19, DAF-3, DMD-5, DUXL-1, DVE-1, EFL-3, EGL-18, EGL-44, EGL-46, EGRH-1, ELT-6, ETS-5, FOS-1, GMEB-1, GMEB-2, HBL-1, HLH-1, HLH-2, HLH-30, K09A11.1, LAG-1, LIM-7, LIN-13, LIN-15B, MDL-1, MML-1, NHR-102, NHR-23, NHR-25, NHR-35, NHR-49, NHR-6, POP-1, SDZ-38, SEL-8, SOX-2, SWSN-7, SYD-9, UNC-120, UNC-3, UNC-37, UNC-62, Y55F3AM.14, Y75B8A.6, ZAG-1, ZFH-2, ZTF-11, ZTF-6 Targeted by: PHA-4 |
Targeting: BLMP-1, CAMT-1, CEBP-1, CEH-13, CEH-20, CEH-39, CEH-43, CES-2, CRH-2, DAF-19, DMD-5, DUXL-1, DVE-1, EFL-3, EGL-44, EGL-46, ELT-6, ETS-5, GMEB-1, GMEB-2, HBL-1, HLH-1, HLH-2, HLH-30, LAG-1, LIN-13, LIN-15B, MDL-1, MML-1, NHR-23, NHR-25, NHR-35, NHR-49, POP-1, SOX-2, SVH-5, SWSN-7, SYD-9, UNC-120, UNC-37, UNC-62, ZAG-1, ZFH-2, ZTF-11 Targeted by: PHA-4 |