WormBase ID: WBGene00003622 WormBase description: Is an ortholog of human RORB (RAR related orphan receptor B) and RORC (RAR related orphan receptor C). Exhibits RNA polymerase II regulatory region sequence-specific DNA binding activity. Is involved in molting cycle and positive regulation of transcription by RNA polymerase II. Localizes to nucleus. Is expressed in gonad; head neurons; and oocyte. Human ortholog(s) of this gene are implicated in idiopathic generalized epilepsy 15. |
Reporter verification: Verified by PCR and sequencing |
Strain name: SYS87 Cross: RW10429 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; gaIs269 (nhr-23::TY1::EGFP::3xFLAG + unc-119(+)) |
Expression pattern: Skin-specific |
Lineage expression pattern 350 stage   |
600 stage  |
3D expression pattern  4-cells  8-cells  15-cells  28-cells  ~50-cells  ~100-cells  ~200-cells  ~350-cells  ~500-cells  ~600-cells  600-cells  bean-stage |
Inferred TF relationships Based on expression similarity (strong, medium, weak): LIN-22, ELT-3, RNT-1, NHR-35, BLMP-1, LIN-26, GMEB-1, C16A3.4, CEH-16, NHR-12, CEH-40, NOB-1, HAM-2, LIN-39, NHR-25, REF-1, ELT-1, NHR-102, CEH-20, BAZ-2, LIN-1, HBL-1, UNC-62, VAB-15, IRX-1, CEH-13, PHP-3, TBX-8, Y56A3A.28, TLP-1, TBX-9, Y75B8A.6, NFI-1, F23B12.7, CEBP-1, TBX-2, CEH-74, CRH-2, SPTF-1, CEH-43 Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined) Targeting: no-data Targeted by: ELT-3, RNT-1, HAM-2, ELT-1, UNC-62, TBX-2, ALY-1, BCL-11, CEH-31, CND-1, ETS-7, HMG-4, LSY-2, MLS-2, NFYA-1, NHR-232, PROS-1, REF-2, BLMP-1, DPL-1, EFL-1, LIN-13, MEP-1, NHR-85, SWSN-7 |
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Targeting: no-data Targeted by: ELT-3, RNT-1, HAM-2, ELT-1, UNC-62, TBX-2, ALY-1, BCL-11, CEH-31, CND-1, ETS-7, HMG-4, LSY-2, MLS-2, NFYA-1, NHR-232, PROS-1, REF-2, BLMP-1, DPL-1, EFL-1, LIN-13, MEP-1, NHR-85, SWSN-7 |
