ALY-1

WormBase ID: WBGene00000120

WormBase description: Is an ortholog of human ALYREF (Aly/REF export factor). Is predicted to have nucleic acid binding activity.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-ACGCTGATCGTCTCATCCAA-3'

Strain name: SYS619

Cross: OP468 x JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs468 (aly-1::TY1::EGFP::3xFLAG(92C12) + unc-119(+))

Expression pattern: Non-specific

Lineage expression pattern

350 stage

600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): NA


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: CEH-39, CEH-43, CES-2, CRH-2, DAF-12, DAF-19, EFL-3, ETS-5, HBL-1, HLH-30, IRX-1, K09A11.1, LIM-7, MEP-1, NHR-102, NHR-23, POP-1, SEL-8, SPR-4, SWSN-7, TBX-2, TLP-1, UNC-37, UNC-39, Y75B8A.6, ZAG-1, ZTF-6

Targeted by: CEH-31, CEH-39, CEH-48, CND-1, COG-1, ELT-2, HAM-2, HLH-1, HLH-8, LIN-13, LIN-32, LSY-2, MEP-1, PHA-4, TBX-2, UNC-120, UNC-55, UNC-62, BLMP-1, C16A3.4, DPL-1, EFL-1, RNT-1, SKN-1

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: CEH-39, CES-2, CRH-2, DAF-19, EFL-3, ETS-5, HLH-30, IRX-1, MEP-1, NHR-23, POP-1, SWSN-7, TBX-2, TLP-1, UNC-37, ZAG-1

Targeted by: CEH-31, CEH-39, CEH-48, CND-1, COG-1, ELT-2, HAM-2, HLH-1, HLH-8, LIN-13, LIN-32, LSY-2, MEP-1, PHA-4, TBX-2, UNC-120, UNC-55, UNC-62, BLMP-1, C16A3.4, DPL-1, EFL-1, RNT-1, SKN-1