WormBase ID: WBGene00006580 WormBase description: Is an ortholog of human ZNF503 (zinc finger protein 503) and ZNF703 (zinc finger protein 703). Is predicted to have repressing transcription factor binding activity. Is involved in positive regulation of transcription by RNA polymerase II. Is expressed in several structures, including body wall musculature; rectal valve cell; somatic nervous system; tail precursor cell; and tail spike. |
Reporter verification: Verified by PCR and sequencing |
Strain name: SYS107 Cross: OP321 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgEx321 (tlp-1::TY1::EGFP::3xFLAG + unc-119(+)) |
Expression pattern: Lineage-specific, Muscle-specific, Transient-expression |
Lineage expression pattern 350 stage |
600 stage |
3D expression pattern 4-cells 8-cells 15-cells 28-cells ~50-cells ~100-cells ~200-cells ~350-cells ~500-cells ~600-cells 600-cells bean-stage |
Inferred TF relationships Based on expression similarity (strong, medium, weak): EGL-5, SYD-9, VAB-7, SNAI-1, RNT-1, LIN-22, PHP-3, LIN-39, VAB-15, NOB-1, HLH-1, CEH-40, CEH-20, UNC-120, PAL-1, NHR-23, UNC-62, NHR-12, CEH-16, GMEB-1, COG-1, LIN-26, M03D4.4, HMBX-1, UNC-30, HBL-1, TBX-11 Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined) Targeting: UNC-62, CRH-2, ELT-3, ETS-4, ETS-5, MDL-1, Y55F3AM.14 Targeted by: RNT-1, HLH-1, UNC-120, UNC-62, COG-1, M03D4.4, ALY-1, CEH-18, CND-1, ELT-1, ELT-2, NFYA-1, PQM-1, TBX-2, TBX-8, UNC-55, LIN-39, VAB-15, BLMP-1, CEH-82, DPL-1, EFL-1, EFL-3, ELT-3, IRX-1, LIN-13, LSY-2, MDL-1, MEP-1, NHR-85, PAX-3, SWSN-7, UNC-130 |
Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined) Targeting: UNC-62, CRH-2, ELT-3, ETS-4, ETS-5 Targeted by: RNT-1, HLH-1, UNC-120, UNC-62, COG-1, ALY-1, CEH-18, CND-1, ELT-1, NFYA-1, TBX-2, TBX-8, UNC-55, LIN-39, VAB-15, BLMP-1, CEH-82, DPL-1, EFL-1, EFL-3, ELT-2, ELT-3, IRX-1, LIN-13, LSY-2, MDL-1, MEP-1, NHR-85, SWSN-7, UNC-130 |