WormBase ID: WBGene00000461 WormBase description: Is an ortholog of human PBX1 (PBX homeobox 1); PBX2 (PBX homeobox 2); and PBX4 (PBX homeobox 4). Is predicted to have DNA binding activity and DNA-binding transcription factor activity. Is expressed in dopaminergic neurons. Human ortholog(s) of this gene are implicated in holoprosencephaly 4. |
Reporter verification: Verified by PCR and sequencing |
Strain name: SYS180 Cross: OP232 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs232 (ceh-40::TY1::EGFP::3xFLAG(92C12) + unc-119(+)) |
Expression pattern: Lineage-specific, Tissue-specific (Skin and Muscle), Transient-expression |
Lineage expression pattern 350 stage ![]() ![]() ![]() ![]() |
600 stage ![]() |
3D expression pattern ![]() 4-cells ![]() 8-cells ![]() 15-cells ![]() 28-cells ![]() ~50-cells ![]() ~100-cells ![]() ~200-cells ![]() ~350-cells ![]() ~500-cells ![]() ~600-cells ![]() 600-cells ![]() bean-stage |
Inferred TF relationships Based on expression similarity (strong, medium, weak): RNT-1, LIN-22, NHR-35, GMEB-1, SYD-9, NHR-23, CEH-16, LIN-39, NHR-12, LIN-26, CEH-20, BLMP-1, UNC-62, CEH-13, BAZ-2, HAM-2, LIN-1, ELT-1, HBL-1, VAB-15, NHR-25, HLH-1, TLP-1, ATF-7, VAB-7, UNC-120, IRX-1, F23B12.7, CEBP-1, Y75B8A.6, NFI-1, M03D4.4, CEH-74, SEL-8 Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined) Targeting: no-data Targeted by: UNC-62, CEH-39, CND-1, ELT-2, TBX-2, UNC-55, ZIP-8, DPL-1, EFL-1 |
Targeting: no-data Targeted by: UNC-62, CEH-39, CND-1, ELT-2, TBX-2, UNC-55, ZIP-8, DPL-1, EFL-1 |