ALY-2

WormBase ID: WBGene00000121

WormBase description: Is an ortholog of human ALYREF (Aly/REF export factor). Is predicted to have nucleic acid binding activity.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-AACACCCAACCGCAGACAG-3'

Strain name: SYS721

Cross: OP217 x JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; ddIs172 (aly-2::TY1::EGFP::3xFLAG(92C12) + unc-119(+))

Expression pattern: Ubiquitous

Lineage expression pattern

350 stage

600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): NA


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: ATF-7, ATFS-1, ATHP-1, BLMP-1, CEBP-1, CEH-20, CEH-38, CRH-2, DAF-3, EFL-1, EGRH-1, EOR-1, ETS-5, FOS-1, HLH-11, HLH-30, LAG-1, LIM-7, LIN-13, MBF-1, MDL-1, MEF-2, MEP-1, MML-1, NHR-10, NHR-102, NHR-35, NHR-49, RCOR-1, SKN-1, UNC-62, Y55F3AM.14

Targeted by: PHA-4

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: ATFS-1, ATHP-1, CEBP-1, CEH-20, CEH-5, CRH-2, DAF-3, EFL-1, EOR-1, ETS-5, HLH-30, LAG-1, LIN-13, MDL-1, MEF-2, MEP-1, MML-1, NHR-10, NHR-49, RCOR-1, UNC-62

Targeted by: PHA-4, TBX-2