WormBase ID: WBGene00004773 WormBase description: Is an ortholog of human SALL1 (spalt like transcription factor 1) and SALL3 (spalt like transcription factor 3). Exhibits RNA polymerase II regulatory region sequence-specific DNA binding activity. Is involved in several processes, including mesodermal cell differentiation; neuroblast differentiation; and transdifferentiation. Localizes to nucleus. Is expressed in several structures, including HSN; M lineage cell; rectal epithelial cell; rectum; and tail hypodermis. Human ortholog(s) of this gene are implicated in several diseases, including Duane-radial ray syndrome; IVIC syndrome; and Townes-Brocks syndrome. |
Reporter verification: Verified by PCR and sequencing |
Strain name: SYS617 Cross: OP57 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs57 (sem-4::TY1::EGFP::3xFLAG(92C12) + unc-119(+)) |
Expression pattern: Muscle-specific |
Lineage expression pattern 350 stage   |
600 stage  |
3D expression pattern  4-cells  8-cells  15-cells  28-cells  ~50-cells  ~100-cells  ~200-cells  ~350-cells  ~500-cells  ~600-cells  600-cells  bean-stage |
Inferred TF relationships Based on expression similarity (strong, medium, weak): EGL-5, HLH-1, UNC-120, M03D4.4 Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined) Targeting: no-data Targeted by: HLH-1, UNC-120, CEH-14, CEH-18, CEH-31, CEH-83, ELT-1, LSY-2, MLS-2, NFYA-1, RNT-1, UNC-42, UNC-55, UNC-62, BLMP-1, C16A3.4, DSC-1, EFL-1, EGL-13, ELT-3, FKH-10, FKH-4, MEP-1, NHR-85, SKN-1, SWSN-7, TBX-2, UNC-86, ZTF-11 |
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Targeting: no-data Targeted by: HLH-1, UNC-120, CEH-18, CEH-31, CEH-83, LSY-2, MLS-2, NFYA-1, RNT-1, UNC-42, UNC-55, UNC-62, BLMP-1, C16A3.4, DSC-1, EFL-1, EGL-13, FKH-4, SKN-1, SWSN-7, TBX-2, UNC-86 |
