WormBase ID: WBGene00011614
WormBase description: Is an ortholog of human NFYA (nuclear transcription factor Y subunit alpha). Is predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Localizes to nucleus. Is expressed in several structures, including excretory cell; gonad; head neurons; oocyte; and somatic nervous system. |
Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-CTCGCCAGAAGTATCTCCACG-3' |
Strain name: SYS166 Cross: OP404 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs404 (nfya-1::TY1::EGFP::3xFLAG + unc-119(+)) |
Expression pattern: Non-specific
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Lineage expression pattern
350 stage
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600 stage
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3D expression pattern  4-cells  8-cells  15-cells  28-cells  ~50-cells  ~100-cells  ~200-cells  ~350-cells  ~500-cells  ~600-cells  600-cells  bean-stage |
Inferred TF relationships
Based on expression similarity (strong, medium, weak): NA
Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)
Targeting: AHR-1, ARID-1, AST-1, ATFS-1, ATHP-1, BLMP-1, CAMT-1, CEBP-1, CEH-13, CEH-16, CEH-20, CEH-27, CEH-32, CEH-38, CEH-39, CEH-43, CEH-44, CEH-45, CEH-48, CEH-6, CFI-1, COG-1, CRH-2, DAF-12, DAF-19, DAF-3, DMD-5, DVE-1, EFL-1, EFL-3, EGL-18, EGL-5, EGRH-1, ELT-1, ELT-3, EOR-1, ETS-5, FOS-1, GMEB-1, HBL-1, HLH-1, HLH-11, HLH-2, HLH-30, IRX-1, K09A11.1, LAG-1, LIM-4, LIM-7, LIN-11, LIN-13, LIN-15B, LIN-31, LIN-39, LSY-2, M03D4.4, MAB-9, MDL-1, MEF-2, MEP-1, MML-1, NHR-10, NHR-102, NHR-23, NHR-35, NHR-49, NOB-1, PAG-3, PAL-1, PAX-3, PHA-4, POP-1, PROS-1, RCOR-1, REF-2, RNT-1, SDZ-38, SEL-8, SEM-2, SEM-4, SKN-1, SOX-2, SPR-4, SPTF-1, SWSN-7, T07F8.4, TAG-68, TBX-2, TLP-1, TTX-1, UNC-120, UNC-130, UNC-3, UNC-30, UNC-37, UNC-42, UNC-62, UNC-86, VAB-15, VAB-3, Y55F3AM.14, Y56A3A.28, Y73E7A.1, Y75B8A.6, ZAG-1, ZFH-2, ZTF-11, ZTF-6
Targeted by: CEH-31, CEH-39, CEH-48, COG-1, HLH-1, LIN-13, MEP-1, PHA-4, RNT-1, TBX-2, UNC-42, BLMP-1, C16A3.4, CEH-8, CEH-82, DPL-1, DSC-1, EFL-1, ELT-3, LSY-2, MDL-1, SWSN-7, UNC-130, UNC-86 |
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 Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)
Targeting: AHR-1, ARID-1, AST-1, ATFS-1, ATHP-1, BLMP-1, CAMT-1, CEBP-1, CEH-13, CEH-16, CEH-20, CEH-27, CEH-32, CEH-39, CEH-43, CEH-45, CEH-5, CEH-6, CEH-74, CRH-2, DAF-19, DAF-3, DMD-5, DPL-1, DVE-1, EFL-1, EFL-3, EGL-5, ELT-1, ELT-3, EOR-1, ETS-5, GMEB-1, HLH-1, HLH-2, HLH-30, IRX-1, K10B3.5, LAG-1, LIM-4, LIM-7, LIN-11, LIN-13, LIN-15B, LIN-31, LIN-39, LSY-2, MAB-9, MDL-1, MEF-2, MEP-1, MML-1, NFYC-1, NHR-10, NHR-23, NHR-35, NHR-49, NOB-1, PAG-3, PAL-1, PAX-3, PHA-4, POP-1, PROS-1, RCOR-1, SEM-4, SKN-1, SOX-2, SPR-4, SPTF-1, SVH-5, SWSN-7, T07F8.4, TBX-2, TLP-1, TTX-1, UNC-130, UNC-30, UNC-37, UNC-42, UNC-62, UNC-86, VAB-15, VAB-3, Y56A3A.28, Y73E7A.1, ZAG-1, ZFH-2
Targeted by: CEH-31, CEH-39, CEH-48, COG-1, HLH-1, LIN-13, MEP-1, PHA-4, RNT-1, TBX-2, UNC-42, BLMP-1, C16A3.4, CEH-8, CEH-82, DPL-1, DSC-1, EFL-1, ELT-3, LSY-2, MDL-1, SWSN-7, UNC-130, UNC-86
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