MBF-1

WormBase ID: WBGene00003148

WormBase description: Is an ortholog of human EDF1 (endothelial differentiation related factor 1). Is predicted to have DNA binding activity. Is expressed in tail.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-GAAAGGTTGGACGCAGAAAG-3'

Strain name: SYS546

Cross: OP426 x JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs426 (mbf-1::TY1::EGFP::3xFLAG + unc-119(+))

Expression pattern: Not expressed in nucleus

Lineage expression pattern

350 stage

600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): FOS-1, CEH-8, PAG-3, PROS-1, Y73E7A.1, UNC-39, TAB-1, CEH-32, HLH-30, HAM-2, SOX-2, SPTF-1, CEH-43, ELT-6, HLH-2, ZIP-8


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: no-data

Targeted by: ELT-2, HLH-1, PHA-4, UNC-120, ALY-2, DPL-1, EFL-1, RNT-1, SWSN-7

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: no-data

Targeted by: PHA-4, CEH-90