SYD-9

WormBase ID: WBGene00044068

WormBase description: Is an ortholog of human ZNF420 (zinc finger protein 420) and ZNF594 (zinc finger protein 594). Is predicted to have RNA polymerase II regulatory region sequence-specific DNA binding activity. Localizes to nuclear speck. Is expressed in ASEL; ASER; muscle cell; nerve ring neurons; and neurons.

Reporter verification: Verified by PCR and sequencing
Primers used to verify fosmid reporter: 5'-TTCCAGGTTCTCATCTCCCG-3'

Strain name: SYS587

Cross: OP434 x JIM113

Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs434 (syd-9::TY1::EGFP::3xFLAG + unc-119(+))

Expression pattern: Not expressed

Lineage expression pattern

350 stage



600 stage

3D expression pattern

4-cells

8-cells

15-cells

28-cells

~50-cells

~100-cells

~200-cells

~350-cells

~500-cells

~600-cells

600-cells

bean-stage

Inferred TF relationships

Based on expression similarity (strong, medium, weak): SNAI-1, EGL-5, LIN-39, VAB-7, HLH-1, VAB-15, CEH-40, UNC-120, M03D4.4, CEH-20, TLP-1, HBL-1, HMBX-1, ATF-7, CES-2, CEBP-1, F23B12.7, Y75B8A.6


Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined)

Targeting: HBL-1, CEBP-1, CEH-44, CEH-48, CRH-2, DAF-19, DMD-5, EGRH-1, ETS-5, HLH-11, HLH-30, K09A11.1, LAG-1, LIM-7, LIN-15B, MDL-1, NHR-102, POP-1, RCOR-1, SDZ-38, SWSN-7, TBX-2, UNC-62, ZTF-6

Targeted by: HLH-1, UNC-120, CEH-14, CEH-31, CEH-34, CEH-36, CEH-48, CEH-6, CEH-83, HMG-4, LIN-32, MEC-3, MLS-2, SPTF-1, UNC-42, UNC-55, UNC-62, ZIP-8, ZTF-11, CEH-8, DSC-1, EGL-13, FKH-8, RNT-1, TBX-2

Based on reannotated ChIP-seq (peaks are assigned to a target if it is located within 2 kb relative to the transcription start site; targets from L1 stage ChIP-seq data are underlined)

Targeting: CEBP-1, CEH-44, CRH-2, DAF-19, DMD-5, ETS-5, HLH-30, LAG-1, LIN-15B, MDL-1, POP-1, RCOR-1, SWSN-7, TBX-2, UNC-62

Targeted by: HLH-1, UNC-120, CEH-31, CEH-34, CEH-36, CEH-48, CEH-6, HMG-4, LIN-32, MEC-3, MLS-2, SPTF-1, UNC-42, UNC-55, UNC-62, ZIP-8, ZTF-11, CEH-8, DSC-1, EGL-13, FKH-8, RNT-1